A field experiment was conducted to study different sources of fertilizer nutrients in different combinations and their effect on growth and yield of cowpea in kharif 2018 and 2019. The results revealed that 100% recommended dose of fertilizers (RDF) + 1% 19:19:19 NPK fertilizer spray at 30 days after sowing (DAS) recorded higher plant height (36.33 and 38.3 cm), number of branches (5.93 and 8.8), pods plant-1 (16.8 and 17.68), seeds pod-1 (15.4 and 16.9), seed yield (1519 and 1688 kg ha-1), which ultimately fetched higher gross return of Rs. 45,570 and 55,704 ha-1, net return of Rs. 19,220 and 28,774 ha-1 and benefit:cost ratio of 1.73 and 2.07 in the first and second year, respectively. The same treatment was found as effective as 100% RDF + seed treatment (Rhizobium + phosphate solubilizing bacteria) + 2% urea spray at 30 DAS in respect of all the observations.